|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
CYP2E1 allele nomenclature
Changes made since the last update (17-Oct-2012)
are marked in red. Allele frequencies: Solus et al., 2004 Links to the NCBI dbSNP homepage are available for
functional SNPs when present in NCBI's database. Nucleotide variations in bold are the major SNPs/alterations
responsible for the phenotype of the corresponding allele. |
Note about CYP2E1 nomenclature
Unfortunately two different nomenclature systems were
developed for the CYP2E1 alleles simultaneously. The authors of both
nomenclature systems have agreed in July 2000 that the nomenclature system
given in this homepage should be the recommended one, see Ingelman-Sundberg
et al. 2001.
Below is a table which will facilitate conversion between the two
systems.
Recommended
nomenclature on the homepage |
Nomenclature
proposed by |
CYP2E1*1A |
CYP2E1*1 |
CYP2E1*1B |
CYP2E1*2 |
CYP2E1*5B |
CYP2E1*3 |
CYP2E1*6 |
CYP2E1*4 |
not included |
CYP2E1*5 |
not included |
CYP2E1*6 |